Hypertrophic cardiomyopathy is most commonly defined by which feature?

Hypertrophic cardiomyopathy is primarily characterized by cardiac hypertrophy, particularly of the left ventricle. This condition involves abnormal thickening of the heart muscle, which can lead to issues with the heart's ability to pump blood effectively and can obstruct blood flow out of the heart. The left ventricle is most commonly affected, as it is responsible for pumping oxygenated blood to the rest of the body.

The presence of hypertrophy can affect the overall function and mechanics of the heart, potentially leading to arrhythmias and an increased risk of sudden cardiac arrest, particularly in young athletes. Understanding this feature is critical in diagnosing and managing patients with hypertrophic cardiomyopathy, as interventions and treatment plans are often based on the degree of hypertrophy and its effects on cardiac function.